I really wish I could use SmartOS, but I couldn't even install some common Python packages without getting a compilation error. Looking such problems up on issue trackers revealed old requests for compatibility with SmartOS, and no follow-up from the developers.
I'm not sure what the recourse is, I just don't know enough about C to fix this myself. I assumed this would be a common enough problem that the solution would be well documented somewhere but there seems to be nothing out there even mentioning the issue.
I'm happy to do all my work in LX-branded zones, and that's certainly better than the alternatives (for my purposes), but having two operating systems still kinda irks me.
On software compatibility unfortunately the actual state (nearly anyone only on GNU/Linux) lead to forget that other OSes exists and many non-POSIX/non-portable features are more and more used anywhere...
That's not an IllumOS/SmartOS or any other unices faults nor something they can really solve...
I recommend using the package manager than building yourself. If something needs to be modified about the source, it will first be patched in the widely used package manager. convincing upstream to take in a patch & then waiting for a new version to be released with that patch takes time.
Ah, I see, thanks. Still, that's a non-starter. Many of the packages I use are not available through any system package manager, and it would preclude using virtualenvs.
OTOH, I desperately want to move away from Python.
Biophysics and biochemistry would both fit the bill.
I would not take the site you linked seriously - it's the ramblings of a crackpot. If you happen to have a biology background and would like to debate this, I'd be happy to elaborate.
They’re not. They are using BGI’s MGISEQ2000 machines. They simply sell the sequencing at a price that doesn’t cover its cost. Both because this is a promotion and because they retain the rights to using your genomic data in research: it’s simply a cheap way for them to get samples.
Is there anything more to it than carving a piece of silica and ligating the adapters to the surface? I mean, I know the process is a bit more involved than that but the patents make it seem relatively straightforward.
It's straightforward in a conceptual sense, but as with most things there are a ton of gotchas and fiddly implementation details, especially if you're doing it in your kitchen/garage. A lot of the difficulty comes with the tedium of maintaining sterile conditions and lots and lots of pipetting.
If you're really interested in DIYBIO there are subreddits and many tuts out there, but fair warning: getting started is easy, but the devil is in the details a heck of a lot more than learning to code.
It can absolutely make things better. I have received lots of good medical advice in this way, with the philosophy that asking alone can't hurt. However I have also weighed the advice as to possible risk. In addition I've tried lots of things that didn't work for me, like diets, sleep patterns, and even some medications.
IMO in order for quality of care to improve across the board, it's important to acknowledge that there is some signal in the noise in situations like this. Overall I think most of us can trust ourselves. Especially if we also have access to medical professionals, many of whom will in practice shrug and say "it's worth a try if you like."
"Disinformation" typically means something intended to mislead[1], as opposed to "misinformation" which is merely wrong, not intentionally malicious. I doubt anyone here is intentionally trying to harm others with their advice...
Yeah, so: Research it, ask professionals about it, weigh the risks, and come to a decision, or don't. It's not like we're just computers who run every piece of input as a command with root privileges. We can engage and use a healthy, non-black-and-white filtering system.
They've asked for help in narrowing a field of information before they explore further. They're not asking for a final direction that they will blindly take.
We're a fairly clever group here, with diverse knowledge. Which means I trust that people asking for advice here realize the need to balance anything posted here with asking a doctor.
Besides, doctors won't tell you anecdotes from other patients. They will present you with the options to treat your problems. Sometimes there are clear answers how to proceed. But when it is less clear, all they can do is tell you the options, and give you pros/cons, and maybe possible outcomes. You then need to make a decision. And asking other people who have been in the same place can be helpful to that decision-making process.
Equating HN community to "web developers" indicates either trolling or you not being experienced with this community and the quality of discussions around here. Also unsubstantial comments that don't add anything to the discussion aren't welcome here.
That's fair, my generalization was pejorative. I meant to say, in a glib way, that this is not a website frequented by 100% licensed physicians and clinical researchers, and is actually mostly not that.
The point is, the OP is essentially saying, "I wish to discard the notion that statistical research is valid and may make medical decisions based on a study with N=1 or 2". I was worried people would show up and offer magical cures as they always do, and lo and behold, there are threads suggesting hypnosis and turmeric.
My main concern with this is that the OP may use a completely arbitrary "cure" and avoid speaking further to doctors about it, so any actual treatments that are developed might be overlooked.
OP here. You are being unkind. I'm not an idiot. I have a doctor. He won't be honest regarding stem cells for legal reasons (they're not fda approved). That said other doctors I know who happen to be experts in stem cells in a totally different medical area have said I should pursue this. HN is one of dozens of avenues I am using to collect information.
No. Working around this takes some effort but is straightforward and uses well-known, existing techniques. There's a lab I know of that considered trying to modify the protein so it could evade the immune system, but they decided against it since they figured the group that published this paper would have too much of a head start and there's no way they'd be able to compete. I'd give it a year or so, and that's assuming none of the other Cas9 or Cas12a variants are already usable.
I've been happy just dual-booting Windows and Linux. Windows 10 is free as long as you don't care about personalizing it, which I definitely don't, since it's just for games. I look forward to having a Linux-only machine but I'm not in any hurry.
It's not about money though, at least for me. I can afford Win 10 just fine, and would also be paying for archlinux and/or Debian if they actually cost anything. But here I am using a free-as-in-beer OS because of other factors. If all games could run in my OS things would just be more practical, regardless of their cost.
Also, consider this from the manager's perspective. They have to ask themselves: if this person has 35 years of experience, they must have a substantial network, so why aren't they just tapping that resource? Not a single person from this applicant's past wants to give them an interview?
Do you know many developers who hang out with management? Most of the engineers I've worked with over my career have not transitioned into management and have no sway as far as the interview process goes.
A company where "I worked with this person in the past and they were good" coming from a run-of-the-mill employee isn't enough to get someone an interview is a company with stupid recruiting practices.
Finding good candidates is expensive and time-consuming. If someone is serving up qualified leads to you on a silver platter, you take them.
Referrals from existing employees are the single highest quality source of candidates for most companies. Many companies even incentivize employees to refer candidates by giving them bonuses if they refer someone who ends up being hired.
Really? I have on many occasions weld a lot of sway on tech hires as senior and lead developer at several companies. It's generally the tech lead/lead developer who has the most say on hiring programmers from my experience.
They proposed one use, which would be to use it as storage for solar/wind power. Perhaps their plan is that when there's excess output from renewables, they'll use electrolysis to generate hydrogen gas from water?
That is exactly the plan. With renewables you have to deploy far more than you need due to capacity factor, so to average 100kW on solar you need to deploy between 300kW and 400kW of capacity. So during the course of the day you will be generating significantly more or significantly less power than required.
Batteries and hydro will help for short term storage of excess power (ie: overnight, during cloud passage) but for long term storage (eg for transport by sea) you need something with higher energy density. For export especially you need high energy density since shipping charged batteries across the planet is going to be extremely inefficient.
The breakthrough this membrane represents is an increase in the “well to wheels” efficiency of the hydrogen economy (which is lower overall than the “pure electric” economy involving BEVs). Having said that, the “well to wheels” efficiency of H2 using Ammonia as a transport medium is under 20%, so it’s really only useful when there is plentiful cheap energy which nobody else has a better use for.
Other uses for plentiful cheap electricity could be (for example) chilling or heating large volumes of water or other thermal mass for air conditioning and industrial processes. If you have large tanks of water you can spend energy chilling (or heating) them when electricity is cheap, then use the chilled water to cool whatever it is you have that is getting too hot (and vice versa for hot water storage).
But if people are willing to pay enough for hydrogen at point of use, there will be an economic case for producing ammonia in Australia to be converted to hydrogen in Japan resulting in 1kWh in Japan costing about the same as 4kWh in Australia.
I did see a video that explained how to correctly handle high pressure gas cylinders, which did teach me some critical things on not getting myself or others killed.
I'm not sure what the recourse is, I just don't know enough about C to fix this myself. I assumed this would be a common enough problem that the solution would be well documented somewhere but there seems to be nothing out there even mentioning the issue.
I'm happy to do all my work in LX-branded zones, and that's certainly better than the alternatives (for my purposes), but having two operating systems still kinda irks me.