I started nicotine after reading through the (probably shoddy) studies on the topic and reading through the anecdotal reports of others experiencing relief with it. (I was desperate, have tried everything I can get my hands on + every kind of dietary intervention.) The experiences seem to be pretty mixed but at least for my form of LC it has made a substantial positive difference.
Out of everything I've tried the only other step I've taken that has made a noticeable difference for me is quitting caffeine. During my acute infection phase it was like a switch flipped that hasn't yet flipped back which completely changed how my body reacts to it. Took me forever to wean off it but doing so has also been a net positive.
NAC + Aspirin is the only thing that helps me but it also makes me feel detached and not hyper as my previous brain state.