I wouldn't get nauseas when I played Overload in VR, but I definitely developed a cold sweat fast. 30 minute sessions were a push and I'd need to recover after. The developers did all the best practices, but there's something inherently mentally stressful about a 6DoF game in VR while you sit still in a chair.
Actually, it's exactly like that! Most games with movement as a physical body, either with or without breast/hip make me car-sick, but this game is mostly taxing mentally because of all of the input. The only game that doesn't affect me, at all and which I can play for many hours is Contractors Showdown.