I apologize for ruining your day, that wasn't my intention. As I stated in my post I don't doubt that obese people have screwed up that signaling over time. Are your cravings off medication worse than mine? Probably. We'd pretty quickly get in to a "Is your green my green?" type discussion talking about that, which obviously has no conclusion. However, I've seen many, many people repeat something along the lines of "Wow, I guess this is what skinny people feel like all the time!" in reference to these medications. I was just pointing out that it absolutely is not how we feel, and I'm one of the fairly rare people out there that can confirm that.